A Practical Approach To Microcalorimetry-Advanced ITC Techniques

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Episode 2 of our Practical Approach to Microcalorimetry Webinar discusses two advanced ITC techniques: temperature variation and coupled protonation. Through temperature variation a user can gain insight into solvation and heat capacity. The other technique addressed is coupled protonation, which can be uncovered by running the same assay in several different buffers at the same pH.

About the Speaker

Colette Quinn received her BA degree in chemistry from Carroll College in Helena, MT. She then began graduate research at Dartmouth College studying toxic metal remediation and essential metal regulation under a Superfund program through the NIEHS, a division of the NIH. The majority of her work was completed using an isothermal titration calorimeter (ITC), which was complimented by a variety of other biophysical techniques. While pursuing her own research, she has also performed ITC contract work for a pharmaceutical company. Shortly after obtaining her Ph.D. in chemistry in 2009, Colette joined TA Instruments as an applications scientist.